Think Gene - Latest Comments in Researchers pinpoint gene mutations responsible for 10 percent of schizophreniahttp://thinkgene.disqus.com/a bio blog about genetics, genomics, and biotechnologyenSat, 31 May 2008 01:42:38 -0000Re: Researchers pinpoint gene mutations responsible for 10 percent of schizophreniahttp://www.thinkgene.com/researchers-pinpoint-gene-mutations-responsible-for-10-percent-of-schizophrenia/#comment-2464307For such a heritable (40%) and research-targeted (<a href="http://208.69.42.138:8080/jiveforums/thread.jspa?threadID=1715&amp;tstart=100" rel="nofollow">NIMH $5MM pledged</a>) disease , it's surprising that so little in the genome is known about schizophrenia. Here's a paper a month ago which suggests rare-variant "microdeletions and microduplications": <a href="http://www.sciencemag.org/cgi/content/abstract/1155174" rel="nofollow">Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia<br></a>Andrew YatesSat, 31 May 2008 01:42:38 -0000